Exploring Botulinum Toxin Injection Resistance: Six Important Insights
The KHROM MEDSPA & WELLNESS team in Brooklyn, New York, works with patients in and around the area to achieve beautiful, healthy skin. This includes offering aesthetic services such as Botox injections, which can help reduce muscle contractions and smooth many dynamic wrinkles such as forehead folds, glabellar lines, and crow’s feet. But did you know that continued use can cause botulinum toxin resistance? Let’s learn more about how this injection can impact you over time and what you can do about it.
Here are six key points regarding resistance to botulinum toxin injections:
1. Botulinum toxin resistance is considered rare.
Resistance to botulinum toxin is uncommon and doesn’t happen to everyone. In fact, only a small percentage of patients naturally develop resistance, meaning the vast majority can use it without issue.
2. Your body is what can cause botulinum toxin resistance.
Resistance happens when the immune system creates antibodies against the toxin. Essentially, your body decides it doesn’t want to play along and creates a defense, making the toxin less effective or completely ineffective.
3. Frequent use of Botox can lead to reduced effectiveness over time if the body develops resistance to it.
Repeated and frequent botulinum toxin treatments increase the likelihood of developing resistance. Spreading out treatments and using the lowest effective dose may reduce the chance of this occurring—so moderation is key!
4. Other botulinum toxin products may be effective, so talk to your doctor about switching to Dysport, Xeomin, or Lytebo.
There are different types of botulinum toxin products on the market, and resistance to one doesn’t necessarily mean resistance to all. Switching products may help if resistance becomes an issue.
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5. The proteins in the injection can impact how it works.
The proteins surrounding the active toxin can sometimes trigger the immune response responsible for resistance. Some newer formulations have been developed with fewer accessory proteins in an effort to reduce this risk.
6. Resistance to botulinum toxin is not always permanent.
Even if resistance does develop, it may not last a lifetime. Over time, the immune system could “forget” its battle with the toxin, allowing people to try it again later. How’s that for a second chance?
What should I do if I need to talk to a professional near me about botulinum toxin resistance?
Botox injections can be a great way to combat the unwanted signs of aging. Still, if you are finding that the injections you receive are not working like they used to, it might be time to talk to our team at KHROM MEDSPA & WELLNESS about alternative treatments that can work. Call 718-521-2912 today to request a visit.
Dr. Khrom completed rigorous training, including a dermatology residency and a prestigious fellowship in procedural dermatology, specializing in Mohs surgery and advanced laser techniques. Recently, she became a GAIN trainer for Galderma and has been recognized as an Elite Practitioner by Merz Aesthetics. Patients trust her sterling reputation, enhanced by her contributions to medical literature and national presentations.
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